THESIS ON MACROCYTIC ANEMIA

Support Center Support Center. Published online Jan Heterogeneous group of disorders acting via various known and unkwown processes can lead to macrocytic anemia. Macrocytosis of the erythrocytes: The prevalence of tropical sprue is also quite great. We observed in our study that being a non vegetarian does not protect against Vitamin B12 deficiency. A significant proportion of non-vegetarians

Support Center Support Center. Macrocytic anemia was diagnosed in patients with 1. Three patients mean age 55 years with a megaloblastic marrow did not respond to vitamin replacement and were found to have myelodysplastic syndrome. The megaloblastic anemias observed were due to either vitamin B 12 deficiency The severity of anemia did not have any correlation with the levels of serum B12 or the degree of macrocytosis. The most common cause of macrocytic anemia was megaloblastic anemia This study was conducted to study the clinical and laboratory parameters in patients with macrocytic anemia and to determine the etiology of macrocytic anemia with special reference to megaloblastic anemia.

Clinico-aetiologic profile of macrocytic anemias with special reference to megaloblastic anemia

Macrocytic anema would be wrongly diagnosed as iron deficiency anemia in many of the situations because thesix similar presentation of variety of anemias. Conclusion Megaloblastic anemia due to Vitamin B 12 or folate deficiency remains the most important cause of macrocytic anemia. Author information Article notes Copyright and License information Disclaimer.

A macroytic approach to macrocytosis. Vitamin B12 deficiency may perhaps produce only low grade macrocytic anemia which when persistant for a prolonged duration there is a rapid detoriation, which has been demonstrated in various case studies.

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thesis on macrocytic anemia

Support Center Support Center. Med Clin North Am. This emphasises the significance of evaluating tropical sprue in a suitable settings to the clinician.

Macrocytosis is common in various clinical settings and it is found in approximately 1. Received Jun 3; Accepted Sep A significant proportion of non-vegetarians In settings with limited laboratory facilities, a therapeutic trial of vitamins B 12 or folic acid is useful in determining the specific vitamin deficiency.

Please review our privacy policy. Upper GI endoscopy with deep duodenal biopsy should be done in all patients with megaloblastic anaemia. The high prevalence of tropical sprue as established in this study has not been revealed in any other study before. Three patients mean age 55 years with a megaloblastic marrow did not respond to vitamin replacement and were found to have myelodysplastic syndrome.

ABC of clinical hematology: The mean age of male and female were Low serum B12 vitamin was leading cause of megaloblastic anemia. Macrocytic anemia is generally classified as megaloblastic or non-megaloblastic anemia.

Status of laboratory testing in the diagnosis of megaloblastic anemia.

Clinico-aetiologic profile of macrocytic anemias with special reference to megaloblastic anemia

Anemia with a hemoglobin of; a. We observed in our study that being a non vegetarian does not protect against Vitamin B12 deficiency.

thesis on macrocytic anemia

To evaluate utilization of bone marrow examination and upper GI endoscopy in diagnosis of megaloblastic anemia. To search for and identification of distinct clinical features may help to diagnose megaloblastic anemia and also may help in the early identification of low levels of B12 or folic acid.

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A practical approach to the differential diagnosis and evaluation of the adult patient with macrocytic anemia. Heterogeneous group of disorders acting via various known and unkwown processes can lead to macrocytic anemia.

Vitamin B 12 deficiency and early rise in MCV. When anemja is no response to iron supplementation after a latent period then only the diagnosis of megaloblastic anemia is offered.

thesis on macrocytic anemia

Post splenectomy and pregnant patients. Although our study had very small number of cases with drug exposure, clinical history of drug intake is essential in evaluating for megaloblastic anemia.

Abstract Purpose of study This study was conducted to study the clinical and laboratory parameters in patients with macrocytic anemia and to determine the etiology of macrocytic anemia with special reference to megaloblastic anemia.

The severity of anemia did not have any correlation with the levels of serum B12 or the degree of macrocytosis. Macrocytosis of the erythrocytes: Tarun Kumar Dutta, Email: Am J Med Sc.