DISSERTATION KORONARE HERZKRANKHEIT

Regarding the coronary risk the remaining polymorphisms were significantly associated neither with an excess risk nor protection. It is therefore expected that MSCT will evolve into the primary diagnostic procedure in patients with a low or intermediate pretest likelihood of CAD. This study analyzes, if elder patients with stable CAD after elective PCI have a worse relative survival than younger patients. The work is publicly available. Apart from the classical risk factors associated arteriosclerosis of the coronary arteries there are indications to a genetic predisposition of this illness, in particular with early manifestation.

The work is publicly available. JavaScript is disabled for your browser. All four age groups suffered from different cardiovascular risk factors. A multivariate Cox regression model underlined the strong influence of age on the prediction of survival. Outcome after elective percutaneous coronary intervention depends on age in patients with stable coronary artery disease [ In addition, the image data acquired for MSCT coronary angiography can be used to analyze cardiac function without additional radiation exposure.

Die vorliegende Arbeit hat sich deshalb das Ziel diissertation, die 1. Noninvasive coronary angiography using multislice computed tomography MSCT has a lower risk and fewer complications compared with invasive catheter-based conventional ddissertation angiography, the current gold standard. Outcome after elective percutaneous coronary intervention depends on age in patients with stable coronary artery disease [ The aim of the present study therefore was to comprehensively evaluate MSCT in terms of detection of coronary artery stenosis, analysis of cardiac function, patient acceptance, and cost effectiveness.

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Coronary artery disease CAD is heerzkrankheit widespread that new developments contributing to a more efficient diagnosis are highly desirable both medically and economically. A multivariate Cox regression model underlined the strong influence of age on the prediction of survival.

  M101 HOMEWORK 2.1

hrzkrankheit In patients with coronary artery disease CAD age is one of the strongest predictors of survival. Some features of this site may not work without it.

dissertation koronare herzkrankheit

Show Simple Item Record. Young, elder and very old patients have a similar relative survival and might therefore have similar benefits from elective PCI. Percutaneous coronary intervention PCI is associated with more complications and worse outcome in elder patients suffering from various co-morbidities. A total of 8, patients with stable CAD between andwho underwent elective PCI were included in this multicenter study.

All four age groups suffered from different cardiovascular risk factors. The work is publicly available. Apart from the classical risk factors associated arteriosclerosis of the coronary arteries there are indications to a genetic predisposition of this illness, in particular with early manifestation. The diagnosis of CAD was placed by means of coronary angiography and both populations were phenotyped extensively regarding anthropometric and laboratory-chemical parameters.

dissertation koronare herzkrankheit

Some features of this site may not work without it. Art von 0, zugrunde gelegen hat. Kosteneffizienz der MSCT zu evaluieren. Polymorphisms in candidate genes as hereditary risk factors for coronary artery disease and percutaneous coronary interventions.

Schnellsuche nach Krankheiten

Regarding the coronary risk the remaining polymorphisms were significantly associated neither with an excess risk nor protection. Outcome after elective percutaneous coronary intervention depends on age in patients with stable coronary artery disease an analysis of relative survival in a multicenter cohort and an OCT substudy. JavaScript is disabled for your browser. Show Simple Item Record. The study population was stratified according to age into four quartiles: In conclusion the observed survival of patients after elective PCI is slightly lower than the expected survival of the age and sex matched general population.

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The other variants of the examined genes did not show significant influence on the procedural risk. These results show relevant advantages for CT coronary angiography not only with regard to the accuracy in detecting coronary artery stenosis but also in terms of patient acceptance and healthcare expenditure.

Refubium – Mehrschicht-Computertomografie in der Diagnostik der koronaren Herzkrankheit

In addition an optical coherence tomography OCT substudy showed different plaque composition and burden within the quartiles. Outcome after elective percutaneous coronary intervention depends on age in patients with stable coronary artery disease: For investigation of hereditery susceptibility factors of coronary artery disease CAD as well as complications to percutaneous coronary interventions PCI we accomplished a large association study with candidate genes of the blood clotting, dissertationn homeostasis and metabolic syndrome.

JavaScript is disabled for your browser. Confirmation in independent populations and further studies presupposed, these hereditery factors could serve for risk stratification of CAD and complications after PCI. It is therefore expected that MSCT will evolve into the primary diagnostic procedure in patients with a low or intermediate pretest likelihood of CAD.

Furthermore, mid-aged patients with stable CAD show a better relative survival than the other age groups. Information for Students Information for Users Imprint.